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SCIENTIFIC PROGRAM

Meeting Summary

Important Announcement

To guarantee precise time-control of scientific program and avoid possible trouble caused by replacement of Notebook computer, all speakers are requested to use the Symposium-provided Notebook computer for their presentation. The speakers must load their PPT file into the Symposium-provided computers with CD disk or flash disk before the session. Copy of any speaker¡¯s PPT files from Symposium-provided computer will be not allowed. The loaded PPT files will be removed from the Symposium-provided computer immediately after each corresponding session.

Detailed Program

May 13, 2008 (Tuesday)

• Registration (9:00am - 8:00pm): Lobby of the Shanghai Galaxy Hotel
• Workshop on Bioluminescence Technology (1:00pm - 5:30 pm): Meeting Room (3rd floor)
• Welcome Reception Sponsored by Promega Corporation (6:00pm - 8:00pm): Cosmos Ballroom 1 and 2 (2nd floor)

May 14, 2008 (Wednesday)

• Opening Ceremony (8:30am - 8:45am): Cosmos Ballroom 1
• Plenary Lectures (8:45am - 10:25am)
• Chairs: Aldo Roda, X. Shen

• PL-1 C.H. Contag (Stanford University, USA) (8:45 am - 9:35 am):
  Molecular imaging with bioluminescence: Revealing mammalian biology and advancing therapeutics
• PL-2 Erkang Wang (Chinese Academy of Sciences, China) (9:35 am - 10:25 am):
  Electrochemiluminescence: Methodology and applications

• Coffee Break (10:25am - 10:40am)
• Session 1. Luciferase-based Bioluminescence (10:40am - 1:05 pm): Cosmos Ballroom 1
• Chairs: Natalia N.Ugarova, Shiao-Chun Tu

• S1-1 John D. Goddard (Canada) (10:40 am - 11:10 am):
  Computational Studies of Firefly Luminescence
• S1-2 Wu Chun (Japan) (11:10 am - 11:40 am):
  Application of the sea-firefly Cypridina bioluminescent system for bioassays
• S1-3 Shiao-Chun Tu (USA) (11:40 am - 12:05 pm):
  An update of bacterial luciferase structure, mechanism, and applications
• S1-4 Natalia N.Ugarova (Russia) (12:05 pm - 12:25 pm):
  Mechanism responsible for the spectral differences in firefly luciferase bioluminescence
• S1-5 Katsunori Teranishi (Japan) (12:25 pm - 12:45 pm):
  Study on ATP-dependent luminescence reaction of the arm light organs of the luminous squid Watasenia scintillans
• S1-6 Saman Hosseinkhani (Iran) (12:45 pm - 1:05 pm):
  Site-directed mutagenesis of Lampyris turkestanicus luciferase: The effect of conserved residue(s) in bioluminescence emission spectra among firefly luciferases

• Session 6. Quantum Dots and Other Inorganic Fluorescent Materials (10:40am - 1:00 pm): Cosmos Ballroom 2
• Chairs: Guoqiang Yang, Xianggui Kong

• S6-1 Xianggui Kong (China) (10:40 am - 11:10 am):
  Luminescent Upconversion Nanoparticle (ULNP) with Photosensitizing Functions to be Used for the Diagnosis and Therapy of Cancer
• S6-2 Hong Zhang (Netherlands) (11:10 am - 11:40 am):
  Charge and energy transfer dynamics between nanoparticles and the influence by organic surrounding
• S6-3 Guoqiang Yang (China) (11:40 am - 12:00 Noon):
  Fluorescence tuning of nanoparticles with different doping level
• S6-4 Zhike He (China) (12:00 Noon - 12:20 pm):
  Quantum dots-ssDNA-fluorescent dye conjugates as bioprobes for specific and sensitive detection of DNase
• S6-5 Hu Shan (China) (12:20 pm - 12:40 pm):
  Fluorescent resonance energy transfer based on quantum dots in antibody-antigen system
• S6-6 X. J. Tu (China) (12:40 pm - 1:00 pm):
  Efficient MXT-QDs fluorescence off-on switch probe for DNA detection in aqueous solution

• Afternoon
• Session 3. Fundmental Aspects of Chemiluminescence (2:30pm - 6:20 pm): Cosmos Ballroom 2
• Chairs: Motoyoshiya Jiro, Hua Cui

• S3-1 Hua Cui (China) (2:30 pm - 3:00 pm):
  Metal nanoparticle-initiated chemiluminescence and electrochemiluminescence
• S3-2 Guonan Chen (China) (3:00 pm - 3:20 pm):
  New techaniques for Electrochemiluminescence
• S3-3 Paul S. Francis (Australia) (3:20 pm - 3:40 pm):
  Chemiluminescence reactions with acidic potassium permanganate: a re-evaluation of the emitting species and new analytical applications
• S3-4 Motoyoshiya Jiro, (Japan) (3:40 pm - 4:00 pm):
  Chemiluminescence of 9-benzylidene-N-methylacridans with electron-donating groups by chemically generated singlet oxygen. Application to metal ion sensing using azacrowned compound
• S3-5 Alexey V. Trofimov (Russia) (4:00 pm - 4:20 pm):
  Generation of High-Energy Chemiluminophores in the Ambient Light

• Tea Break (4:20pm - 4:40pm)

• S3-6 K Yamaguchi (Japan) (4:40pm - 5:00pm):
  Theoretical studies of charge-transfer-induced luminescence in molecular and bimolecular systems
• S3-7 D.V. Kazakov (Russia) (5:00pm - 5:20pm):
  A new bright chemiluminescent reaction: interaction of acetone with solid-phase potassium monoperoxysulfate in the complex of eropium nitrate
• S3-8 Chun-Feng Duan (China) (5:20pm - 5:40pm):
  Polymer-stabilized gold nanocluster enhanced luminol chemiluminescence in neutral solutions
• S3-9 Xiaolin Yang (China) (5:40pm - 6:00pm):
  A novel synergistic agent to the enhancers for HRP-H2O2 based chemiluminescence and its application in immunoassay
• S3-10 Ali Al-Mourabit (France) (6:00pm - 6:20pm):
  Chemiluminescent oxidative rearragement of diketopiperazines involved in the biomimetic synthesis of marine pyrrole-2-aminoimidazole metabolites

• Session 8. Instrumentation and New Methods (2:30pm - 6:00 pm): Cosmos Ballroom 1
• Chairs: Keith Wood, Berthold A

• S8-1 Keith Wood (Promega Corporation, USA) (2:30pm - 3:00pm):
  Optimization of a luminescent biosensor for intracellular cAMP
• S8-2 A Berthold (Germany) (3:00pm - 3:20pm):
  New luminescent multi-enzyme assays for genomics and drug discovery applications
• S8-3 Frank Fan (USA) (3:20pm - 3:40pm):
  High throughput screening and live cell imaging using luciferase biosensors
• S8-4 Lampinen Jorma (Finland) (3:40pm - 4:00pm):
  Miniaturization of luminometric assays: Optimizing the performance of common luminescent assays in 384-, and 1536-well plate formats
• S8-5 O.A. Gandelman (UK) (4:00pm - 4:20pm):
  BART: smart biochemistry, bright bioluminescence, low-cost hardware

• Tea Break (4:20pm - 4:40pm)

• S8-6 Youmei Wang (China) (4:40pm - 5:00pm):
  A novel electrochemiluminescent biosensor based on conducting polymer/chitosan for ultrasensitive detection of hydrogen peroxide
• S8-7 Chiwai Wong (China) (5:00pm - 5:20pm):
  Using a luciferase based screening assay to identify Traditional Chinese Medicine targeting nuclear hormone receptors
• S8-8 Arne Lundin (Sweden) (5:20pm - 5:40pm):
  Protein kinase assay with improved kinetics

May 15, 2008 (Thursday)

• Plenary Lectures (8:30am - 10:10 am): Cosmos Ballroom 1
• Chairs: Akio Tsuji, XR Zhang

• PL-3 Minoru Isobe (Nagoya University, Japan) (8:30am - 9:20am):
  Molecular Mechanism of Squid Bioluminescence
• PL-4 Aldo Roda (Alma Mater Studiorum-University of Bologna, Italy) (9:20 am - 10:10 am):
  Analytical challenges for luminescence-based point-of-care testing devices in biomedical diagnostics

• Coffee Break (10:10am - 10:30am)
• Session 4 (I). Application of Chemiluminescence (10:30 am - 12:10pm): Cosmos Ballroom 1
• Chairs: Osamu Nozaki, Jin-Ming Lin

• S4-1 Jin Ouyang (China) (10:30am - 10:50am):
  Improved direct chemiluminescent imaging detection of serum proteins in polyacrylamide gels using organic dyes
• S4-2 He-you Han (China) (10:50am - 11:10am):
  A Novel Method for the Determination of Furazolidone by Flow-injection Post Chemiluminescence
• S4-3 Osamu Nozaki (Japan) (11:10am - 11:30am):
  Determination of pyrogallol by imidazole chemiluminescence coupled to the peroxidase embedded organic monolith reactor
• S4-4 Xun Shen (China) (11:30am - 11:50am):
  Chemiluminescence study on the upregulation of NADPH oxidase activity by thioredoxin reductase in vascular endothelial cells

• Session 9 (I). Fluorescence, Phosphorescence and Ultraweak Luminescence (10:30am - 12:00 Noon): Cosmos Ballroom 2
• Chairs: Dinesh Shah, Da Xing

• S9-1 Da Xing (China) (10:30am - 11:00am):
  Luminescence methods for non-invasive detection of plant physiology
• S9-2 Yu Xiang (China) (11:00am - 11:20am):
  Rhodamine B-quinoline-8-amide as a fluorescent "ON" probe for Fe3+ in acetonitrile
• S9-3 J. N Chen (China) (11:20am - 11:40am):
  Distribution of Fluorescent Dissolved Organic Matter in the South China Sea
• S9-4 Irina O. Osina (Russia) (11:40am - 12:00 Noon):
  Fluorescence from S2-level of complexes of tryptophan with europium (III) in water-ethanol solution

• Afternoon
• Poster Session I (1:30pm - 3:00pm): Cosmos Ballroom 1 and 2
• Tea Break (2:40pm - 3:00pm)
• Session 5. Luminescence Imaging (3:00pm - 6:10 pm): Cosmos Ballroom 1
• Chairs: C.H. Contag, ZJ. Cui

• S5-1 Hoshino Hideto (Japan) (3:00pm - 3:30pm):
  Development of BRET-based Auto-illuminated Fluorescent-protein (BAF) and Application to live-cell imaging
• S5-2 Andrew L. Miller (Hong Kong) (3:30pm - 4:00pm):
  The use of aequorins to image Ca2+ signaling during zebrafish development: Throwing light on embryonic pattern formation
• S5-3 Manfred Hennecke (Germany) (4:00pm - 4:30pm):
  Non-invasive Molecular Imaging: A Comparison of various technologies with special reference to optical imaging
• S5-4 Hirobumi Suzuki (Japan) (4:30pm - 4:50pm):
  Bioluminescence imaging of intracellular calcium dynamics by photoprotein, Obelin
• S5-5 Ryutaro Akiyoshi (Japan) (4:50pm - 5:10pm):
  The measurement of cytosolic ATP during apoptosis: bioluminescence imaging at the single cell level
• S5-6 Lubov Y. Brovko (Canada) (5:10pm - 5:30pm):
  Bioluminescence imaging of bacteria-host interplay: interaction of E.coli with epithelial cells
• S5-7 Ming-Qun Xu (USA) (5:30pm - 5:50pm):
  Generation of Site-specific Labeled Protein Probes for Live Cell Imaging
• S5-8 Yoko Hatta-Ohashi (Japan) (5:50pm - 6:10pm):
  Visualization of sequential response in intra-cellular signal transduction cascade by fluorescence and luminescence imaging in the same living cell

• Session 4 (II). Application of Chemiluminescence (3:00pm - 5:10 pm): Cosmos Ballroom 2
• Chairs: Willy Baeyens, Yaning Liu

• S4-6 Zhijuan Cao (China) (3:00pm - 3:20pm):
  G-rich sequence-functionalized polystyrene microsphere-based instantaneous derivatization for the chemiluminescent amplified detection of DNA
• S4-7 Ken Yokawa (Japan) (3:20pm - 3:50pm):
  Use of Cypridina luciferin analog for assessing the monoamine oxidase-like superoxide-generating activities of two peptide sequences corresponding to the helical copper-binding motif in human prion protein and its model analog
• S4-8 Yanchun Wei (China) (3:50pm - 4:10pm):
  Quantitative detection of singlet oxygen with chemiluminescence probe during photodynamic reaction
• S4-9 Cun Lin (Japan) (4:10pm - 4:30pm):
  Chemiluminescent and electron spin resonance spectroscopic measurements of reactive oxygen species generated in water treated with titania-coated photocatalytic fibers
• S4-10 Jalil Mehrzad (Iran) (4:30pm - 4:50pm):
  Excessive extracellular chemiluminescence and necrosis of neutrophils in bovine neonates and potentially supportive role of vitamin C
• S4-11 Jianxiu Du (China) (4:50pm - 5:10pm):
  Chemiluminescence determination of rutin using a micelle-sensitizing N-bromosuccinimide-H₂O₂ reaction

May 16, 2008 (Friday)

• Plenary Lectures (8:30am - 10:10 am): Cosmos Ballroom 2
• Chairs: Larry Kricka, Xiaolin Yang

• PL-5 Zhujun Zhang (Shaanxi Normal University, China) (8:30am - 9:20am):
  Molecular imprinted polymer-based chemiluminescence imaging sensor
• PL-6 J. Woodland Hastings (Harvard University, USA) (9:20am - 10:10am):
  Sixty years of discoveries and applications in bioluminescence: from ATP to reporter genes

• Coffee Break (10:10am - 10:30am)
• Session 2. Photoproteins-based Bioluminescence (10:30am - 12:30pm): Cosmos Ballroom 2
• Chairs: Vysotski, Zhijie Liu

• S2-1 Zhijie Liu (China) (10:30am - 11:00am):
  Crystal structure of coelenterazine-binding protein from Renilla muelleri at 1.72 Å
• S2-2 Eugene S. Vysotski (Russia) (11:00am - 11:30am):
  The diversity of coelenterazine-dependent bioluminescent proteins
• S2-3 T. Hirano (Japan) (11:30am - 11:50am):
  Chemiexcitation mechanism for Cypridina (Vargula) and Aequorea bioluminescence
• S2-4 E.V. Eremeeva (Russia) (11:50am - 12:10pm):
  The kinetics of coelenterazine binding with apoobelin and apoaequorin
• S2-5 L. A. Frank (Russia) (12:10pm - 12:30pm):
  Coelenterazine-dependent bioluminescent proteins as the effective labels in immunoassay

• ">Session 7. Environmental, Evolutionary and Ecological Aspects of Bio- and Chemi-luminescence (10:30am - 1:00pm): Cosmos Ballroom 1
• Chairs: V. Vadim, J. Mallefet

• S7-1 Viviani Vadim (Brazil) (10:30am - 11:00am):
  CCD Imaging of Basal Bioluminescence in larval fireflies: clues on the anatomical origin of beetle bioluminescence
• S7-2 J. M Claes (Belgium) (11:00am - 11:20am):
  Bioluminescence of sharks, a case study: Etmopterus spinax
• S7-3 Xin-xin Huang (China) (11:20am - 11:40am):
  Construction of Recombinant Luminescence Bacteria Vector to Evaluate the Genetoxic of Environment Pollutant
• S7-5 J. Mallefet (Belgium) (11:40am - 12:00 noon):
  Nervous control of luminescence in Ophionereis schayeri (Ophiuroidea, chinodermata)
• S7-6 Xinhua Fu (China) (12:00 noon - 12:20pm):
  The fine structure of larval light organ in aquatic firefly luciola lei
• S7-8 Alexander A. Gusev (Russia) (12:20pm - 12:40pm):
  Change of expression efficiency of natural and cloned lux-operon in conditions of famine
• S7-9 Changying Niu (China) (12:40pm - 1:00pm):
  Temperature-dependence of bioluminescence of Australian glow-worm Arachnocampa flava Harrison (Diptera: Keroplatidae)

• Afternoon
• Poster Session II (2:00pm - 3:30pm): Cosmos Ballroom 1 and 2
• Tea Break (3:10pm - 3:30pm)
• Session 9 (II). Fluorescence, Phosphorescence and Ultraweak Luminescence (3:30pm - 5:50 pm): Cosmos Ballroom 2

• S9-5 R.H. Zhu (China) (3:30pm - 3:50pm):
  Novel ¦Â-Cyclodextrin Modified Organic Polymeric Monolithic Substrate for Solid Phase Extraction-Room Temperature Phosphorescence
• S9-6 Yanli Wei (China) (3:50pm - 4:10pm):
  Protein conformation changes study based on its room temperature phosphorescence
• S9-7 Weijun Jin (4:10pm - 4:30pm):
  Phosphorescent properties of 2-bromoquinoline-3-boronic acid in sodium deoxycholate aggregates and potential application in recognition of carbohydrates
• S9-8 Na Shao (China) (4:30pm - 4:50pm):
  Spiropyran-based Fluorescent Probes for Biological Species
• S9-9 Qijian Yang (China) (4:50pm - 5:10pm):
  The superweek luminescence of plant and its ultraweak photon image
• S9-10 Wen-li Chen (China) (5:10pm - 5:30pm):
  Delayed fluorescence study on the abiotic stress induced progressive senescence of Arabidopsis
• S9-11 Lingrui Zhang (China) (5:30pm - 5:50pm): Delayed fluorescence and optical molecule imaging techniques for detecting the stress response of plant to high temperature

• Farewell Banquet Sponsored by China Medical Technology (7:30pm - 9:00pm)

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